Clinical Validation Across Key Areas of Use

Beauty from Within: Skin, Hair & Nails

84-Day Clinical Study in Aging Skin – CosmoDerma, 2025

A placebo-free, 12-week clinical trial assessed the effects of MESOPOROSIL® in 22 women aged 40–66 with visible signs of skin aging and dryness.

Results showed:

  • 72.7% of users reported firmer, more hydrated, and more elastic skin by Day 84
  • 68.2% noted improved radiance and reduction in fine lines
  • Nail strength and hair quality improved over time
  • No adverse effects; 100% tolerance, no aftertaste, no gastric distress
  • 77.3% were satisfied with results and willing to continue using the product

This study confirms MESOPOROSIL® as an effective, science-backed beauty-from-within ingredientwith excellent tolerability and compliance.
Source: [CosmoDerma 2025, Mohta et al.][30†Publication Cosmoderma]

Bone Health & Recovery

Minor Vertebral Fracture Study – PharmaNutrition, 2023

50 patients with “minor” traumatic vertebral fractures were treated either with:

  • Conventional brace therapy alone
  • Or brace + MESOPOROSIL® + vitamin D3 + K2 (SilDì® formula)

After 2 months:

  • 84.6% of the treated group showed complete bone edema resolution (vs. 15.4% in the control)
  • Allowed early removal of spinal orthosis, improving mobility and quality of life
  • MRI confirmed superior bone healing
  • No side effects reported; safe and well tolerated

These results support MESOPOROSIL®’s key role in accelerating bone regeneration, collagen production, and improving patient recovery.
Source: [PharmaNutrition 2023, Arpino et al.][28†Nutraceutical supplementation]

Enhanced Vitamin & Collagen Utilization

In Vitro Study – MG-63 Osteoblast Cells, 2024

Findings under both normal and glucocorticoid-damaged conditions:

  • +77.6% increase in collagen type I synthesis
  • +48.4% increase in osteocalcin production
  • Enhanced protection from bone loss under steroid-induced stress
  • Improved cell viability and osteoblast function

These cellular-level results show MESOPOROSIL® enhances bone-building, collagen-forming pathways, and supports nutrient synergy with D3, K2, and calcium.
Source: [PharmaNutrition 2024, Motta et al.][29†Pharmanutrition]